Drug Delivery Solutions LLC

Consultants

Books

Svenson, S., (Ed.), “Polymeric Drug Delivery II - Polymeric Matrices and Drug Particle Engineering”, ACS Symposium Series Vol. 924, American Chemical Society, Washington, DC, 2006.

Svenson, S., (Ed.), “Polymeric Drug Delivery I - Particulate Drug Carriers”, ACS Symposium Series Vol. 923, American Chemical Society, Washington, DC, 2006.

Svenson, S., (Ed.), “Carrier-Based Drug Delivery”, ACS Symposium Series Vol. 879, American Chemical Society, Washington, DC, 2004.

 

Book Chapters

Svenson, S.; Tomalia, D.A. "Dendrimers and Hyperbranched Nanospheres with Medical Applications" in "Nano-particles for Pharmaceutical Applications", Domb, A.J.; Tabata, Y.; Ravi Kumar, M.N.V. (Eds.), American Scientific Publishers, Stevenson Ranch, CA, 2007, pp. 233-256.

Svenson, S.; Tomalia, D.A. “Dendrimers as Nanoparticulate Drug Carriers” in “Nanoparticulates as Drug Carriers”, Torchilin, V.P. (Ed.), Imperial College Press, London, UK, 2006, pp. 277-299.

Svenson, S. “Advances in Polymeric Drug Matrices and Drug Particle Engineering”, in “Polymeric Drug Delivery II - Polymeric Matrices and Drug Particle Engineering”, Svenson, S. (Ed.), ACS Symposium Series Vol. 924, American Chemical Society, Washington, DC, 2006, pp. 2-11.

Svenson, S. “Advances in Particulate Polymeric Drug Delivery”, in “Polymeric Drug Delivery I - Particulate Drug Carriers”, Svenson, S. (Ed.), ACS Symposium Series Vol. 923, American Chemical Society, Washington, DC, 2006, pp. 2-11.

Svenson, S. “Overview: Carrier-Based Drug Delivery”, in “Carrier-Based Drug Delivery”, Svenson, S. (Ed.), ACS Symposium Series Vol. 879, American Chemical Society, Washington, DC, 2004, pp. 2-23.

Svenson, S. “The Role of Steric Constraints and Intermolecular Interactions in the Formation of Surfactant Phases”, in “Reactions and Synthesis in Surfactant Systems”, Texter, J. (Ed.), Surfactant Science Series Vol. 100, Marcel Dekker 2001, pp. 667-713.

Fuhrhop, J.-H.; Svenson, S. “The Stereochemistry of Lipid Aggregates and their Growth and Separation Processes”, in “Kinetics and Catalysis in Microheterogeneous Systems”, Grätzel, M.; Kalyanasundaram, K. (Eds.), Surfactant Science Series Vol. 38, Marcel Dekker 1991, pp. 273-301.

Fuhrhop, J.-H.; Svenson, S.; Boettcher, C.; Bach, R.; Schnieder, P. “Stereo- and Regioselective Aggregation of N-Octylaldonamides to Amphiphilic Fibres” in “Molecular Mechanisms in Bioorganic Processes”, Bleasdale, C.; Golding, B.T. (Eds.), Proc. Roy. Soc. Chem., Joint Perkin Div., Cambridge 1990, pp. 65-82.

 

Journal Articles

Svenson, S. “Dendrimers as Versatile Platform in Drug Delivery Applications”, Eur. J. Pharm. Biopharm., submitted, 2008 (invited review for special issue).

Svenson, S.; Chauhan, A.S.  “Dendrimers for Enhanced Drug Solubilization”, Nanomedicine, accepted, 2008 (invited review).

Svenson, S., Chauhan, A.S., Zhuravel, M.A. “Poly(etherhydroxylamine) PEHAM Dendrimer Nanoparticles for Combination Therapy and Diagnostic”, 35th Annual Meeting of the Controlled Release Society (CRS) 2008.

Svenson, S.; Chauhan, A.S.; Reyna, L.A.; Tomalia, D.A. “PEHAM Dendrimers for Drug Delivery Applications”, Proc. 34th Annual Meeting of the Controlled Release Society (CRS) 2007, 63.

Svenson, S. "Dendrimers", Kirk-Othmer Encyclopedia of Chemical Technology, 5th Edition, John Wiley & Sons, Inc., 2007, 26, 786-812 (invited review).

Chauhan, A.S.; Svenson, S.; Reyna, L.A.; Tomalia, D.A. “Solubility Enhancement of Poorly Water Soluble Molecules Using Dendrimers”, Material Matters 2007, 2(1), 24-26 (invited communication).

Tomalia, D.A.; Reyna, L.A.; Svenson, S. “Dendrimers as Multi-purpose Nanodevices for Oncology Drug Delivery and Diagnostic Imaging”, Biochem. Soc. Trans. 2007, 35(1), 61-67.

Svenson, S., Chauhan, A.S., Reyna, L.A., Tomalia, D.A “STARBURST® and Priostar™ Dendrimers for Controlled Drug Delivery Applications”, Polymer Preprints 2006, 47(2), 150-151.

Svenson, S.; Tomalia, D.A. ”Dendrimers in Biomedical Applications – Reflections on the Field”, Adv. Drug Deliv. Rev. 2005, 57, 2106-2129 (invited review/commentary).

Svenson, S. “Controlling Surfactant Self-Assembly”, Curr. Opin. Colloid Interface Sci. 2004, 9, 201-212 (invited review).

Svenson, S. “Self-Assembly and Self-Organization: Important Processes – But Can We Predict Them?”, J. Dispersion Sci. Technol. 2004, 25, 101-118 (Feature Review).

Elder, E. J.; Hitt, J. E.; Rogers, T. L.; Tucker, C. J.; Saghir, S.; Svenson, S.; Evans, J. C. “Particle Engineering of Poorly Water Soluble Drugs by Controlled Precipitation”, Proc. Am. Chem. Soc., Div. Polym. Mater.: Science and Engineering 2003, 89, 741.

Svenson, S.; Tucker, C.J.; Hitt, J.E.; Elder, E.J.; Evans, J.C.; Saghir, S.A. “Particle Size Control to Improve the Oral Bioavailability of Drugs”, Proc. 30th Annual Meeting of the Controlled Release Society (CRS) 2003, 328.

Svenson, S.; Tucker, C.J.; Hitt, J.E.; Elder, E.J.; Evans, J.C.; Saghir, S.; Rosenberg, S. “Enhanced Oral Bioavailability of Drug Particles Made Via an Emulsion Template”, Proc. Controlled Release Society Winter Symposium & 11th Symposium on Recent Advances in Drug Delivery Systems 2003, 50.

Messerschmidt, C.; Svenson, S.; Stocker, W.; Fuhrhop, J.-H. “Rearrangements of N-Octyl-D-gluconamide Fibers and Bilayers on Gold and Silicon Surfaces”, Langmuir 2000, 16, 7445-7448.

Di Meglio, C.; Rananavare, S.B.; Svenson, S.; Thompson, D.H. “Bolaamphiphilic Phosphocholines: Structure and Phase Behavior in Aqueous Media”, Langmuir 2000, 16, 128-133.

Svenson, S.; Prud’homme, R.K. “Unexpected Changes of the Shear Viscosity in Mixtures of Hydrophobically Modified Hydroxyethylcellulose and CTAB/NaSal at Low and High Temperatures”, Proc. Am. Chem. Soc., Div. Polym. Mater.: Science and Engineering 1999, 81, 503-504.

Svenson, S.; Messersmith, P.B. “Formation of Polymerizable Phospholipid Nanotubules and Their Transformation into a Network Gel”, Langmuir 1999, 15, 4464-4471. (Cover graphic of Langmuir 15, No. 22, October 1999)

Fuhrhop, J.-H.; Svenson, S.; Böttcher, C.; Träger, O.; Demoulin, C.; Schnieder, P.; Messerschmidt, C.; Ruhlmann, L.; Zimmermann, J. “Non-Covalent Chiral Fibres in Aqueous Gels and Their Functionalization”, Bull. Mater. Sci. 1999, 22, 307-312.

Svenson, S.; Thompson, D.H. “Facile and Efficient Synthesis of Bolaamphiphilic Tetraether Phosphocholines”, J. Org. Chem. 1998, 63, 7180-7182.

Svenson, S.; Kirste, B.; Fuhrhop, J.-H. “A CPMAS 13-C NMR Study of Molecular Conformations and Disorder of N-Octylhexonamides in Microcrystals and Supramolecular Assemblies”, J. Am. Chem. Soc. 1994, 116, 11969-11975.

Svenson, S.; Schäfer, A.; Fuhrhop, J.-H. “Conformational Effects of 1,3-syn-Diaxial Repulsion and 1,2-Gauche Attraction Between Hydroxy Groups in Monomolecular N-Octyl-D-hexonamide Solutions. A 13-C and 1-H NMR Spectroscopic Study”, J. Chem. Soc., Perkin Trans. 2 1994, 1023-1028.

Svenson, S.; Köning, J.; Fuhrhop, J.-H. “Crystalline Order in Probably Hollow Micellar Fibers of N-Octyl-D-gluconamide”, J. Phys. Chem. 1994, 98, 1022-1028.

Svenson, S. “Conformational Analysis of Open-chain N-Alkylhexonamides in their Supramolecular Assemblages”, Ph.D. Dissertation, Free University Berlin, Germany, 1993.

Fuhrhop, J.-H.; Svenson, S.; Luger, P.; André, C. “Micellar Fibers with Crystalline Surfaces and their Co-Crystallization”, Supramol. Chem. 1993, 2, 157-171.

André, C.; Luger, P.; Svenson, S.; Fuhrhop, J.-H. “The X-ray Crystal Structure of N-(n-Octyl)-D-Talonamide and a Consideration of its Hydrogen Bonding Scheme”, Carbohydr. Res. 1993, 240, 47-56.

André, C.; Luger, P.; Svenson, S.; Fuhrhop, J.-H. “The Crystal Packing of N-(n-Octyl)-D-Gulonamide Containing Tail-To-Tail Sheets Compared to its Glucon-Diastereomer Showing Head-To-Tail Arrangement”, Carbohydr. Res. 1992, 230, 31-40.

Fuhrhop, J.-H.; Svenson, S.; Boettcher, C.; Rössler, E.; Vieth, H.-M. “Long-Lived Micellar N-Alkylaldonamide Fiber Gels. Solid State NMR and Electron Microscopic Studies”, J. Am. Chem. Soc. 1990, 112, 4307-4312.

Svenson, S. “Electron Microscopic Studies of Long-Lived Fiber Gels Complemented by Solid State 2-H NMR Spectroscopy”, Proc. of the XIIth Int. Congress of Electron Microscopy 1990, 852-853.

 

Presentations and Seminars

Svenson, S., Chauhan, A.S., Reyna, L.A. Poly(etherhydroxylamine) PEHAM Dendrimers for Enhanced Drug Solubilization”, 7th International Symposium on Polymer Therapeutics, Valencia, Spain, May 2008 (invited talk).

Svenson, S. “Priostar™ Dendrimers in Drug Delivery Applications”, 5th International Dendrimer Symposium (IDS-5), Toulouse, France, August 2007 (invited talk).

Svenson, S., Chauhan, A.S., Reyna, L.A., Tomalia, D.A. “PEHAM Dendrimers for Drug Delivery Applications”, 34th Annual Meeting of the Controlled Release Society, Long Beach, CA, July 2007 (podium presentation).

Svenson, S., Chauhan, A.S., Reyna, L.A., Tomalia, D.A “STARBURST® and Priostar™ Dendrimers for Controlled Drug Delivery Applications”, 232nd ACS National Meeting, San Francisco, CA, September 2006 (invited talk).

Svenson, S., Chauhan, A.S., Reyna, L.A., Tomalia, D.A “STARBURST® and Priostar™ Dendrimers for Enhanced Drug Solubilization”, 232nd ACS National Meeting, San Francisco, CA, September 2006 (oral).

Svenson, S., Chauhan, A.S., Reyna, L.A., Tomalia, D.A “Dendrimers: A Platform for Custom-Designed Drug Delivery”, Particles 2006, Orlando, FL, May 2006 (invited talk).

Svenson, S. “Dendrimers - A Promising Approach to Tailored Carriers in Drug Delivery Applications”, 3rd International Nanomedicine and Drug Delivery Symposium, Baltimore, MD, September 2005 (invited talk).

Svenson, S. “Dendrimers Made via Self-Assembly: A Promising Approach to Tailored Carriers in Drug Delivery Applications”, Gordon Research Conference on Chemistry of Supramolecules & Assemblies, Colby College, ME, June 2005 (invited talk).

Svenson, S.; Swanson, D.R.; Tomalia, D.A. “Ion Conductivity in Polyether-Dendronized Polymers”, 228th ACS National Meeting, Philadelphia, PA, August 2004 (oral).

Svenson, S.; Kubasiak, L.A.; Tomalia, D.A. “The Role of Dendrimers in Biology: From Biomimicry to Drug Delivery and Nanomedical Applications”, Nano/Bio Convergence 2004, Cambridge, MA, March 2004 (keynote lecture).

Svenson, S.; DeMattei, C.R.; Huang, B.; Tomalia, D.A. ”Dendrimers Made Via Self-Assembly and Self-Organization”, Particles 2004, Orlando, FL, March 2004 (invited talk).

Svenson, S.; Swanson, D.R.; Tomalia, D.A. “Drug Delivery from Dendritic Architecture”, Gordon Research Conference on Chemistry of Supramolecules & Assemblies, Andover, NH, July 2003 (poster).

Svenson, S.; Tucker, C.J.; Hitt, J.E.; Elder, E.J.; Evans, J.C.; Saghir, S.A.; Rosenberg, S. “Enhanced Oral Bioavailability of Drug Particles Made via a Template Emulsion”, CRS Winter Symposium and 11th International Symposium on Recent Advances in Drug Delivery Systems, Salt Lake City, UT, March 2003 (podium presentation).

Svenson, S. “Encapsulation and Drug Delivery”, University of Waterloo, Department of Chemistry, Waterloo, Canada, November 2002, (invited seminar).

Svenson, S.; Tucker, C.J.; Hitt, J.E.; Elder, E.J.; Evans, J.C.; Saghir, S.A.; Rosenberg, S. Nano-particles of Poorly Water Soluble Drugs Prepared via Template Emulsions”, 2002 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting & Exposition, Toronto, Canada, November 2002 (poster).

Hitt, J.E.; Curtis, C.A.; Fransen, K.L.; Kupperblatt, G.B.; Rogers, T.L.; Scherzer, B.D.; Svenson, S.; Tucker, C.J.; Wilson, D.L.; Young, T.J. “Nanoparticles of Poorly Water Soluble Drugs Made via a Continuous Precipitation Process”, 2002 American Association of Pharmaceutical Scientists (AAPS) Annual Meeting & Exposition, Toronto, Canada, November 2002 (poster).

Svenson, S.; Tucker, C.J. “Template Emulsions: A Successful Process to Produce Nanoparticles of Poorly Soluble Drugs”, 76th ACS Colloid & Surface Science Symposium, Ann Arbor, MI, June 2002 (oral).

Svenson, S.; Tucker, C.J.; Hitt, J.E. “Nanoparticles of Poorly Water Soluble Drugs Made Via a Continuous Precipitation Process”, 76th ACS Colloid & Surface Science Symposium, Ann Arbor, MI, June 2002 (poster).

Svenson, S.; Tucker, C.J.; Hitt, J.E. “Nanoparticles of Poorly Water-Soluble Drugs Prepared Via Template Emulsions, Dow Spring Science & Technology Meeting 2002, Midland, MI, May 2002 (poster).

Svenson, S.; Tucker, C.J.; Hitt, J.E. “Nanoparticles of Poorly Water Soluble Drugs Prepared Via Template Emulsions”, Particles 2002, Orlando, FL, April 2002 (invited talk).

Svenson, S.; Hitt, J.E.; Tucker, C.J. “Nanoparticles of Poorly Water Soluble Drugs Made Via a Continuous Precipitation Process”, Particles 2002, Orlando, FL, April 2002 (poster).

Svenson, S. “Carrier-Based Drug Delivery”, Indiana University-Purdue University Indianapolis (IUPUI), Department of Chemistry, Indianapolis, IN, March 2002 (invited seminar).

Svenson, S.; Tucker, C.J.; Hitt, J.E. “Nanoparticles of Poorly Water Soluble Drugs Prepared via Template Emulsions”, Gordon Research Conference on Drug Carriers in Medicine & Biology, Ventura, CA, February 2002 (poster).

Svenson, S.; Ladika, D.; Nelson, P. “Enhanced Bioavailability of Poorly Water Soluble Drugs via Controlled Precipitation”, 2nd Dow Chemical Interfacial Science & Application Symposium, Midland, MI, November 2001 (oral).

Svenson, S.; Tucker, C.J.; Green, D.P.; Hitt, J.E.; Evans, J.C. “Enhanced Bioavailability of Poorly Water-Soluble Drugs”, Dow Spring Science & Technology Meeting 2001, Midland, MI, May 2001 (poster).

Svenson, S.; Prud'homme, R.K. “Cetyltrimethylammonium Bromide/Sodium Salicylate Rodlike Micelles – A Well Understood System?”, Gordon Research Conference on Chemistry of Supramolecules & Assemblies, Henniker, NH, August 1999 (poster).

Svenson, S.; Prud'homme, R.K. “Unexpected Changes of the Shear Viscosity in Mixtures of Hydrophobically Modified Hydroxyethylcellulose and CTAB/NaSal at Low and High Temperatures”, 218th ACS National Meeting, New Orleans, LA, August 1999 (oral).

Svenson, S.; Prud'homme, R.K. “CTAB/NaSal Micelles –Temperature-Dependent Changes of the Shear Viscosity”, Gordon Research Conference on Ion-Containing Polymers, Newport, RI, June 1999 (poster).

Svenson, S.; Messersmith, P.B. “Solid State Deuterium NMR Studies of a Polymerizable Phospholipid Hydrogel Formed from a Transient Nanotubule Phase”, 217th ACS National Meeting, Anaheim, CA, March 1999 (oral).

Svenson, S.; Messersmith, P.B. “Formation of a Polymerizable Phospholipid Hydrogel from a Transient Nanotubule Phase”, 216th ACS National Meeting, Boston, MA, August 1998 (oral).

Svenson, S.; Thompson, D.H. “Vectorial Electron Transfer and Na+ Flux Acceleration in Gramicidin-Containing Bolaamphiphile Vesicles”, Gordon Research Conference on Chemistry of Supramolecules & Assemblies, Newport, RI, August 1997 (poster).

Svenson, S.; Schulz, A. “From Micelles to Organized Supramolecular Structures Formed by a Macrocyclic Bola-amphiphile”, 69th Colloid & Surface Science Symposium, Salt Lake City, UT, June 1995 (oral).

Svenson, S.; Fuhrhop, J.-H. “A CP/MAS C-13 NMR Study of Molecular Conformations and Disorder of N-Octyl-hexonamides in Microcrystals and Supramolecular Assemblies”, 28th Great Lakes Regional ACS Meeting, La Crosse, WI, June 1995 (oral).

Svenson, S. “Conformational Analysis of Amphiphiles in their Supramolecular Fiber Assemblies”, Birmingham, UK, July 1994 (poster).